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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Murugkar, Anupa | - |
| dc.contributor.author | Padhye, Subhash | - |
| dc.contributor.author | Vorobjeva, Lena | - |
| dc.date.accessioned | 2013-08-21T05:51:07Z | - |
| dc.date.available | 2013-08-21T05:51:07Z | - |
| dc.date.issued | 2003-08 | - |
| dc.identifier.issn | 0975-0975(Online); 0376-4710(Print) | - |
| dc.identifier.uri | http://hdl.handle.net/123456789/20708 | - |
| dc.description | 1861-1864 | en_US |
| dc.description.abstract | Pre-formed iron(III) complexes of naphthoquinone thiosemicarbazone ligands, viz. 2-hydroxy-1,4-naphthoquinone-1-thiosemicarbazone (HNQTSC) and 2-thiosemicarbazido-1,4- naphthoquinone (TSCNQ) have been synthesized, characterized by various physical techniques and their potential for inhibition of ribonucleotide reductase (RDR) enzyme, crucial for DNA synthesis, has also been evaluated. It is observed that the pre-formed iron(III) complexes possess higher RDR inhibitory activity than the respective free ligands. | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | NISCAIR-CSIR, India | en_US |
| dc.rights |  CC Attribution-Noncommercial-No Derivative Works 2.5 India | en_US |
| dc.source | IJC-A Vol.42A(08) [August 2003] | en_US |
| dc.title | Pre-formed iron-thiosemicarbazone chelates as ribonucleotide reductase inhibitors | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | IJC-A Vol.42A(08) [August 2003] | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCA 42A(8) 1861-1864.pdf | 871.77 kB | Adobe PDF | View/Open |
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