Synthesis, structure and reactivity of zirconium(IV), vanadium(IV), cobalt(II), nickel(II) and copper(II) complexes derived from carbohydrazide schiff base ligands

Abstract

A series of polydentate schiff base ligands have been prepared by the condensation of carbohydrazide, H₂N-NH-CONH-NH₂, with various aldehydes and the isolated ligands characterized by elemental analysis and spectral methods. In order to investigate the coordination behaviour of these ligands, metal complexes of the type M(acac)_x L[M = Zr(IV), VO(IV), Co(II), Ni(II) and Cu(II); L = Schiff base ligands; x = 0 or 2] have been prepared from the reaction of these ligands with their corresponding metal acetylacetonates. On the basis of analytical and spectral data, square antiprism, square pyramid and square planar structures have been proposed. The biological activities of all isolated ligands and their metal complexes have been studied by screening the compounds against organisms such as <i>E. coli, S. aureus, A. niger </i>and C. <i>albicans </i>and the results have been compared.