Synthesis, characterization and peroxidase activity of binuclear complexes of 2,6-bis(2-hydroxybenzylidene hydrazone )-4-methyl phenol

Abstract

The homo- and heterobinuclear complexes of Fe(II), Ni(II) and Cu(II) with 2,6-bis(2-hydroxybenzylidene hydrazone)-4-methyl phenol have been synthesized by template and non-template condensation methods. The probable structures of the complexes having general formula [MM'LCl(H₂O)₄].nH₂O (where M=M'=Fe, Ni or Cu; M = Fe, M' = Ni or Cu; H₃L = ligand; n = 0,1, 2 or 4) have been proposed on the basis of elemental analyses, molecular weight determination, conductance measurements, magnetic moment, ESR and

spectroscopic data. From spectroscopic studies, it has been concluded that coordination occurs through phenolic oxygen after deprotonation, nitrogen of azomethine and chlorine atom; the two metals being bridged through oxygen and chlorine atom. Of the three binucleating complexes of iron namely, (Fe, Fe), (Fe, Ni) and (Fe, Cu) tested for peroxidase activity, only (Fe, Cu) complex is found to be active.