Synthesis and structural investigation of biologically active complexes of lanthanide with chlorpromazine

Abstract

Fourteen new complexes of lanthanide(III) nitrate with chlorpromazine as ligand have been synthesised with the general formula [Ln(CP)₂(NO₃)₂]NO₃ where Ln = La, Ce, Pr, Nd, Sm, Eu, Gd, Th, Dy, Ho, Er, Tm, Yb, Lu and CP = chlorpromazine. The complexes have been characterized on the basis of their elemental analysis, molar conductance, magnetic susceptibility, spectral, thermal and XRD data. Electronic spectral parameters(β, b^1/2

,δ%, η) have been calculated for praseodymium(III), neodymium(III) and erbium(III) complexes. Probable structures for the complexes have been proposed on the basis of their physico-chemical studies. The fungicidal activity of the ligand and some of the isolated

lanthanide(III) nitrate complexes have been tested.