Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/21552| Title: | Synthesis of pyrazoline, pyrimidine and 1,5-benzodiazepine derivatives of 1,8-naphthyridine and evaluation of antibacterial activity |
| Authors: | Mogilaiah, K Sudhakar, G Rama |
| Issue Date: | Mar-2003 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A series of 1-aryl:2,2-bis-(1,8-naphthyridin-2-yl)ethenes 4, 5-aryl-3-methyl-4-(1 ,8-naphthyridin-2-yl)-1-phenyl-2-pyrazolines 5, 5,6-dihydro-6-aryl-4-methyl-5-(1,8-naphthyridin-2-yl)-2-thioxopyrimidines 6 and 2,3-dihydro-2-aryl-4-methyl-3-(1,8-naphthyridi n-2-y l)-1 H-1,5-benzodiazepines 7 have been synthesized from 2-aminonicotinaldehyde 1 via α-(1,8-naphthyridin-2-yl) banzai acetones 3. The benzalacetones 3 have been readily obtained by the condensation of 1 with 3-arylideneacetylacetones 2. These compounds have been characterized on the basis of elemental analyses, IR,1H NMR and MS. The compounds 4, 5 and 6 have been screened for their antibacterial activity. |
| Page(s): | 636-640 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.42B(03) [March 2003] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 42B(3) 636-640.pdf | 897.87 kB | Adobe PDF | View/Open |
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.