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http://nopr.niscpr.res.in/handle/123456789/21557| Title: | Synthesis of 6-aryl-2-(2-phenyl-1,8-naphthyridine-3-carbonyl)-4,5-dihydropyridazin- 3(2H)-ones |
| Authors: | Mogilaiah, K Kankaiah, G |
| Issue Date: | Mar-2003 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Condensation of 2-phenyl-1,8-naphthyridine-3-carboxylic acid hydrazide 1 with β-aroylpropionic acids 2 in ethanol affords the corresponding N-(2-phenyl-1,8-naphthyridine-3-carbonyl)-β-aroylpropionic acid hydrazones 3, which on treatment with gl. acetic acid undergo facile cyclization to yield 6-aryl-2-(2-phenyl 1,8-naphthyridine 3-carbonyl)-4,5-di hydro-pyridazin-3(2H)-ones 4. The compounds 4 have been tested for their antibacterial activity. The structures of the products have been delineated by elemental analyses and spectral studies. |
| Page(s): | 658-660 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.42B(03) [March 2003] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 42B(3) 658-660.pdf | 566.61 kB | Adobe PDF | View/Open |
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