Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/21659
Title: Microwave-assisted synthesis and biological activities of some bridgehead nitrogen heterocycles
Authors: Hirpara, H M
Sodha, V A
Trivedi, A M
Khatri, B L
Parikh, A R
Issue Date: Jul-2003
Publisher: NISCAIR-CSIR, India
Abstract: The synthesis of some 6-aryl-3-pyridin-4-yl-5,6-dihydro-[1,2,4]triazolo [3,4-b]  [1,3,4] thiadiazoles 3a-v by the condensation of 4-amino-5-pyridin-4-yl-4H-[1,2,4]-trizole-3-thiol 1 with various aromatic aldehydes 2 in the presence of catalytic amount of p-toluenesulphonicacid using microwave irradiation & conventional heating has been reported. Considerable increase in the rate of the reaction has been observed with better yields by microwave irradiation using DMF as energy transfer medium. The synthesized compounds have been characterized on the basis of elemental and spectral studies and screened for their antibacterial and antifungal activities against several microbes.
Page(s): 1756-1759
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.42B(07) [July 2003]

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