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http://nopr.niscpr.res.in/handle/123456789/21674Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Khan, M S Y | - |
| dc.contributor.author | Hasan, S M | - |
| dc.date.accessioned | 2013-10-07T11:12:45Z | - |
| dc.date.available | 2013-10-07T11:12:45Z | - |
| dc.date.issued | 2003-08 | - |
| dc.identifier.issn | 0975-0983(Online); 0376-4699(Print) | - |
| dc.identifier.uri | http://hdl.handle.net/123456789/21674 | - |
| dc.description | 1970-1974 | en_US |
| dc.description.abstract | Several new flavones/flavanones and 5'-substituted-2'-hydroxy chalcones have been synthesised through Claisen Schmidt condensation. 5-Chloromethyl-2-hydroxy acetophe none 1 on condensation with various aromatic aldehydes yields chalcones 2a and 2b, which on cyclisation in presence of SeO2 give corresponding flavones 2c and 2d respectively. Compound 3 is obtained from 1 by reacting with o-toluidine. Further condensation of 3 with different aromatic aldehydes gives the corresponding chalcone/flavone derivatives 3a-e. The synthesised flavonoid derivatives are evaluated for their antiinflammatory activity on carrageenan induced paw edema in rats and in vitro antibacterial activity. The results have been encouraging. | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | NISCAIR-CSIR, India | en_US |
| dc.rights |  CC Attribution-Noncommercial-No Derivative Works 2.5 India | en_US |
| dc.source | IJC-B Vol.42B(08) [August 2003] | en_US |
| dc.title | Synthesis, antiinflammatory and antibacterial activity of some new flavonoidal derivatives | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | IJC-B Vol.42B(08) [August 2003] | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 42B(8) 1970-1974.pdf | 876.81 kB | Adobe PDF | View/Open |
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