Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/21678| Title: | Michael additions on isoxazole derivatives under solvent-free conditions |
| Authors: | Rajanarendar, E Ramesh, P Karunakar, D |
| Issue Date: | Aug-2003 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Knoevenagel condensation of 3,5-dimethyl-4-nitro- isoxazole 1 with aromatic aldehydes in solid state in the presence of piperidine gives 3-methyl-4-nitro-5-styryl-isoxazoles 2 in excellent yields within few minutes. Michael addition of active methylene compounds 3 to 2 in piperidine affords β-diketones 4. Similarly1 reacts with chalcones 5 in piperidine very efficiently to give Michael adducts 6 in excellent yields with substantial reduction in reaction time under solvent- free conditions. |
| Page(s): | 1994-1996 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.42B(08) [August 2003] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 42B(8) 1994-1996.pdf | 587.65 kB | Adobe PDF | View/Open |
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