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http://nopr.niscpr.res.in/handle/123456789/21704| Title: | Synthesis of β-casomorphin employing Fmoc-amino acid chlorides and t- butyldimethylsilyloxy benzotriazole (TBDMS-OBt) |
| Authors: | Tantry, Subramanyam J Mathad, Raveendra I Babu, Vommina V Suresh |
| Issue Date: | Sep-2003 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Coupling of Fmoc-amino acid chlorides can be carried out using t-butyldimethylsilyloxy benzotriazole, the reaction being carried out in organic medium. No addition of base is required. The coupling is fast and racemization free. The workup and isolation of product are easy. Thus, the synthesis of β-casomorphin (Tyr-Pro-Phe-Pro-Gly) is accomplished. |
| Page(s): | 2104-2108 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.42B(09) [September 2003] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 42B(9) 2104-2108.pdf | 239.65 kB | Adobe PDF | View/Open |
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