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http://nopr.niscpr.res.in/handle/123456789/21770| Title: | Studies on quinazolines: Part II-Synthesis and antimicrobial evaluation of some 2,2-disubstituted-3,3-biquinazolin-4(3H)-ones |
| Authors: | Wasfy, A A F |
| Issue Date: | Dec-2003 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | N-(2-Styryl-, 2-p-chlorostyryl-or 2-p-nitrostyryl-4-oxo-3H-quinazolin-3-yl)-2-aminobenzamides 6a-c react with triethyl orthoesters to furnish some new 2-styryl-, 2-p-chlorostyryl- or 2-p-nitrostyryl-2-substituted-3,3-biqui-nazolin-4(3H)ones (7a-c-9a-c). An alternative synthesis of (7-9)b has been accompli shed by reaction of acetylanthranil with 2-amino-2-styryl-, 2-p-chlorostyryl- or 2-p-nitrostyryl-quinazolin-4(3H)-ones 4a-c. The synthesised products are tested for antimicrobial activities using methaqualone as reference standard. |
| Page(s): | 3102-3107 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.42B(12) December 2003] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 42B(12) 3102-3107.pdf | 1.06 MB | Adobe PDF | View/Open |
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