Condensed heterocyclic systems containing bridgehead nitrogen atom: Synthesis and antimicrobial activity of s-triazolo[3,4-b][1, 3,4] thiadiazines, thiazolo[3,2-b]-s-triazoles and isomeric thiazolo[2,3-c]-s-triazoles

Mohan, Jag

Welcome to NIScPR Online Periodicals Repository

You can now access full text articles from research journals published by CSIR-NIScPR! Full text facility is provided for all nineteen research journals viz. ALIS, AIR, BVAAP, IJBB, IJBT, IJCA, IJCB, IJCT, IJEB, IJEMS, IJFTR, IJMS, IJNPR, IJPAP, IJRSP, IJTK, JIPR, JSIR & JST. NOPR also hosts three Popular Science Magazines viz. Science Reporter (SR), Vigyan Pragati (VP) & Science Ki Duniya (SKD) and a Natural Products Repository (NPARR).

Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/21827

Full metadata record

DC Field	Value	Language
dc.contributor.author	Mohan, Jag	-
dc.date.accessioned	2013-10-10T11:03:12Z	-
dc.date.available	2013-10-10T11:03:12Z	-
dc.date.issued	2002-02	-
dc.identifier.issn	0975-0983(Online); 0376-4699(Print)	-
dc.identifier.uri	http://hdl.handle.net/123456789/21827	-
dc.description	403-406	en_US
dc.description.abstract	The synthesis of 2-p-fluorophcnyl-5-p-bromophenylthiazolo[3,2-b]-s-triazole 5 has been achieved starting from 3-p-fluorophenyl-5-mercapto-s-triazole 3. Compound 3 on condensation with p-bromophenacyl bromide gave the ketone 4 which on cyclization with PPA affords thiazolo[3,2-b]-s-triazole 5 and not the isomeric thiazolo[2,3-c]-s-triazole 7. This has been established by an unequivocal synthesis of 7 through POCl₃ cyclization of 2-p-fluorobenzoylhydrazino-4-pbromophenyl thiazole hydrobromide 6. However the condensation of 4-amino-5-mercapto-3-p-fluorophenyl-s-triazole 8 with p-chlorophenacyl bromide furnishes 7H-6-p-chlorophenyl-3-p-fluorophenyl-s-triazolo[3,4,-b] [1,3,4] thi adiazine 9 in one step only. The diuretic, antibacterial and antifungal activities of these compounds have also been evaluated.	en_US
dc.language.iso	en_US	en_US
dc.publisher	NISCAIR-CSIR, India	en_US
dc.rights	CC Attribution-Noncommercial-No Derivative Works 2.5 India	en_US
dc.source	IJC-B Vol.41B(02) [February 2002]	en_US
dc.title	Condensed heterocyclic systems containing bridgehead nitrogen atom: Synthesis and antimicrobial activity of s-triazolo[3,4-b][1, 3,4] thiadiazines, thiazolo[3,2-b]-s-triazoles and isomeric thiazolo[2,3-c]-s-triazoles	en_US
dc.type	Article	en_US
Appears in Collections:	IJC-B Vol.41B(02) [February 2002]

Files in This Item:

File	Description	Size	Format
IJCB 41B(2) 403-406.pdf		782.21 kB	Adobe PDF	View/Open

Show simple item record