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http://nopr.niscpr.res.in/handle/123456789/21845Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Srivastava, Arun K | - |
| dc.contributor.author | Shakeel, Mohd | - |
| dc.contributor.author | Khan, Arbab A | - |
| dc.date.accessioned | 2013-10-10T11:59:13Z | - |
| dc.date.available | 2013-10-10T11:59:13Z | - |
| dc.date.issued | 2002-02 | - |
| dc.identifier.issn | 0975-0983(Online); 0376-4699(Print) | - |
| dc.identifier.uri | http://hdl.handle.net/123456789/21845 | - |
| dc.description | 436-439 | en_US |
| dc.description.abstract | QSAR studies, using structural parameters
such as equalized electronegativity 'Xeq', molecular connectivity ‘1 b'
and hydrophobicity ‘logP' on a novel series of ω-amino alkanoic acid derivatives
of betulinic acid, have been discussed. Anti HIV-1 activity of these compounds both
in CEM-4 and MT-4 cell cultures is found to correlate well with steric 1 b
as well as electronic Xeq parameters. The
presence of an amide function is found to be
important for activity.
| en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | NISCAIR-CSIR, India | en_US |
| dc.rights | CC Attribution-Noncommercial-No Derivative Works 2.5 India | en_US |
| dc.source | IJC-B Vol.41B(02) [February 2002] | en_US |
| dc.title | QSAR studies on anti HIV-1 N-substituted betulinic acid amides | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | IJC-B Vol.41B(02) [February 2002] | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 41B(2) 436-439.pdf | 720.25 kB | Adobe PDF | View/Open |
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b'
and hydrophobicity ‘logP' on a novel series of ω-amino alkanoic acid derivatives
of betulinic acid, have been discussed. Anti HIV-1 activity of these compounds both
in CEM-4 and MT-4 cell cultures is found to correlate well with steric 1