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http://nopr.niscpr.res.in/handle/123456789/22132| Title: | Synthesis of 4-(1-phenylmethyl-5-imidazolyl)-1,4-dihydropyridines as calcium channel antagonists |
| Authors: | Hadizadeh, F Shafiee, A Kazemi, R Mohammadi, M |
| Issue Date: | Dec-2002 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | o-Nitrophenyl group of nifedipine has been replaced with 2-alkylthio-1-phenylmethyl-5-im idazolyl substituent. Starting from dihydroxyacetone and phenylmethylamine hydrochloride, 2-alkythio-l-phenylmethyl-5-formylimidazole 3 is first synthesized and subsequently used in synthesizing symmetrical (5a-f) and asymmetrical (6a,b) dihydropyridines. |
| Page(s): | 2679-2682 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.41B(12) December 2002] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 41B(12) 2679-2682.pdf | 782.02 kB | Adobe PDF | View/Open |
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