Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/22453| Title: | α-Dehydro β-amino acid derivatives as turn inducer: Synthesis of potential HIV protease inhibitors based on structural mimicry† |
| Authors: | Rajesh, S Srivastava, Jyoti Banerji, Biswadip Iqbal, Javed |
| Issue Date: | Nov-2001 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | α-Dehydro β-amino
acid derivatives
derived di- and tripeptides 4-7 adopt eight-member turn conformations in
CDCl3 solutions. These peptides show similar hydrogen bonding
characterstics as compared to the corresponding  -proline containing peptides 8. Thus the dehydro
β-amino acid
derived tripeptides 7 may behave as the structural mimic of the -proline containing tripeptides
8c which are structural analogues of HIV protease inhibitors. |
| Page(s): | 1029-1032 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.40B(11) [November 2001] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 40B(11) 1029-1032.pdf | 738.53 kB | Adobe PDF | View/Open |
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