Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/22458| Title: | Preparation, anti protozoal and antibacterial evaluation and mutagenicity of some metronidazole derivatives |
| Authors: | Kapoor, V K Dubey, Sonal Mahindroo, Neeraj |
| Issue Date: | Jan-2000 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Preparation of metronidazole derivatives 2-5 is described and the results of antimicrobial evaluation and mutagenicity are given. Compounds 2 and 5 at higher concentrations show better anti protozoal activity than the parent drug. When tested against few strains of Bacteroides fragilis, an anaerobic microorganism, compound 2 is found to be active on four strains, compound 4 to be active against two strain whereas 3 and 5 are effective against only one strain. In mutagenicity assay 4 is found to be less mutagenic than the parent drug. |
| Page(s): | 27-30 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.39B(01) [January 2000] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 39B(1) 27-30.pdf | 814.69 kB | Adobe PDF | View/Open |
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