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Title: Evaluation of antioxidant potential of ethanolic extracts of selected species of Selaginella
Authors: Sivaraman, A
Johnson, M
Parimelazhagan, T
Irudayaraj, V
Keywords: Selaginella;Antioxidant;Phenols;Flavonoids;Spike mosses
Issue Date: Sep-2013
Publisher: NISCAIR-CSIR, India
IPC Code: Int. cl. (2011.01)−A61K 36/00, A61P 17/18
Abstract: The purpose of the present study was to investigate the amount of total phenolics, flavonoids, tannins and in vitro antioxidant properties of ethanolic extracts of different Selaginella species, viz. Selaginella involvens (Sw.) Spring., Selaginella intermedia (Bl.) Spring., Selaginella inaequalifolia (Hook. & Grev.) Spring. and Selaginella tenera (Hook. & Grev.) Spring. The antioxidant activities were evaluated by measuring the ability of the extracts to scavenge the DPPH+, ABTS+, FRAP, metal chelating and phosphomolybdenum assays. The maximum extractable total phenolics were recorded in S. involvens (128.41 mg GAE/g), tannins and flavonoids were present in S. intermedia (67.46 and 184.44 mg GAE/g, respectively). Among the four different ethanolic extracts of Selaginella species, the maximum DPPH+ free radical scavenging activity was exerted by S. involvens (IC50 71.84 µg/mL). Highest activity of ABTS+ assay was observed in S. involvens (2281.48 µmol TE/g) and S. tenera registered the higher Fe2+ chelation (1352.77 µmol Fe (II)/mg). Maximum metal chelating activity was exhibited by S. inaequalifolia (4.56 mg EDTA equiv/g) and the strongest phosphomolybdenum reduction was observed in the ethanolic extracts of S. tenera (26.1 g AA/100 g). The results of the study clearly suggest that Selaginella species are a natural source of antioxidants and it validates the folkloric usage.
Page(s): 238-244
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.4(3) [September 2013]

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