Synthesis and antibacterial activity of some novel 4-oxo-1,3-thiazolidines, 2-oxoazetidines and 5-oxoimidazolines: Part VI

Abstract

Several methyl 2-{2-[4-oxo-3-(arylcarbonylamino)-1,3-thiazolidin-2-yl] phenoxy} acetates <b>3a-h</b>, methyl 2-{2-[3-chloro-4-oxo-1-(arylcarbonylamino)azetidin-2-yl]phenoxy} acetates <b>4a-e</b>, methyl 2-(2-{[5-oxo-2-phenyl-1-(arylcarbonylamino)-2-imidazolin-4-ylidene]methyl} phenoxy)acetates <b>6a-i</b> and methyl 2-{2-[(5-oxo-2-phenyl-l-{[(arylamino)thioxomethyl] amino}-2-imidazolin-4-ylidene)methyl] phenoxy} acetates <b>7a-p</b> have been synthesized. All the synthesized compounds have been evaluated for their <i>in vitro </i>growth inhibitory activity against several microbes like <i>E.coli</i>,<i> S.aureus </i>and <i>Salmonella typhi para A. </i>The structures of these compounds have been established on the basis of elemental analysis and spectral data.