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http://nopr.niscpr.res.in/handle/123456789/22565Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Jain, Niveta | - |
| dc.contributor.author | Krishnamurty, H G | - |
| dc.date.accessioned | 2013-10-23T09:44:13Z | - |
| dc.date.available | 2013-10-23T09:44:13Z | - |
| dc.date.issued | 2000-11 | - |
| dc.identifier.issn | 0975-0983(Online); 0376-4699(Print) | - |
| dc.identifier.uri | http://hdl.handle.net/123456789/22565 | - |
| dc.description | 817-821 | en_US |
| dc.description.abstract | The stilbenoid constituents of Combretum caffrum possess pronounced antineoplastic and antimitotic activities. The most potent agents are R (-) combretastatin 1, and combretastatins A-1 to A-4. A novel and simple method for the synthesis of ±1 and isocombretastatin 5 in which an appropriately substituted 1, 3-diarylpropanoid is transformed into a stilbenoid is described. The key step involves the alkali induced rearrangement of chalcone epoxide 9 to α-hydroxy acid 10 and that is followed by oxidative decarboxylation and reduction. | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | NISCAIR-CSIR, India | en_US |
| dc.rights |  CC Attribution-Noncommercial-No Derivative Works 2.5 India | en_US |
| dc.source | IJC-B Vol.39B(11) [November 2000] | en_US |
| dc.title | An expedient synthesis of racemic combretastatin and isocombretastatin | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | IJC-B Vol.39B(11) [November 2000] | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 39B(11) 817-821.pdf | 956.87 kB | Adobe PDF | View/Open |
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