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Title: Role of Arogh, a polyherbal formulation to mitigate oxidative stress in experimental myocardial infarction
Authors: Suchalatha, S
Thirugnanasambandam, P
Maheswaran, E
Devi, C S Shyamala
Keywords: Arogh;Myocardial infarction;Oxidative stress;Polyherbal formulation;Rat
Issue Date: Feb-2004
Publisher: NISCAIR-CSIR, India
Abstract: Antioxidant role of Arogh in isoproterenol induced myocardial infarction in rats has been studied. The activity of heart tissue antioxidants like glutathione, superoxide dismutase, Catalase, glutathione peroxidase and glutathione-s-transferase were significantly decreased in isoproterenol administered group. The activity of ceruloplasmin and levels of glutathione, vitamins E and C were also found to be substantially decreased in serum with a concomitant rise in lipid peroxide levels after isoproterenol exposure to rats. The synergistic effect of Arogh pretreatment, significantly suppressed the alterations induced by isoproterenol alone in rats.
Page(s): 224-226
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.42(02) [February 2004]

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