Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/23396| Title: | In vitro effects of organophosphate pesticides on rat erythrocytes |
| Authors: | Singh, Mohan Sandhir, Rajat Kiran, Ravi |
| Keywords: | Erythrocytes;Hemolysis;K+ leakage;Lipid peroxidation;Organophosphates |
| Issue Date: | Mar-2004 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | In vitro effects of various organophosphate pesticides (dimethoate, chlorpyrifos, ethion and monocrotophos) were studied on hemolysis, K+ leakage and lipid peroxidation in rat erythrocytes. All the four pesticides increased hemolysis and K+ leakage from erythrocytes, that was concentration and time dependent. On the contrary, there was decrease in lipid peroxidation in erythrocyte membrane. Effect of pesticides on lipid peroxidation could be due to pesticide itself abstracting protons or interacting with free radicals rather than polyunsaturated fatty acids (PUFA), thereby protecting the latter against peroxidation. |
| Page(s): | 292-296 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Appears in Collections: | IJEB Vol.42(03) [March 2004] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 42(3) 292-296.pdf | 1.06 MB | Adobe PDF | View/Open |
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