The stem cell in the umbilical cord blood is not related to volume and nucleated cell count

Abstract

The percent CD 34⁺ cells in umbilical cord tremendously var-ied from sample to sample. Study conducted on 100 cryopre-served samples for their volume, nucleated cell count and CD 34⁺ cell count showed no correlation between the three. Correlation study between volume and nucleated cell count showed poor cor-relation, where as correlation between volume and CD 34⁺, nucle-ated cell count and CD 34⁺ cell count showed no/negative correla-tion. Graphical representation of volume vs. nucleated cell count, volume vs. CD 34⁺ cell count, and nucleated cell count vs. CD 34⁺ cell count show the same results. These results have important bearing in umbilical cord blood banking, since sample accep-tance/rejection at present is based only on volume of cord blood collected, which instead should be based on the number of CD 34⁺ stem cells.