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http://nopr.niscpr.res.in/handle/123456789/23572| Title: | Mentha piperita (Linn) leaf extract provides protection against radiation induced alterations in intestinal mucosa of Swiss albino mice |
| Authors: | Samarth, R M Saini, M R Maharwal, J Dhaka, A Kumar, Ashok |
| Issue Date: | Nov-2002 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Intestinal protection in mice against radiation injury by M. piperita (1 g/kg body weight/day) was studied from day 1 to day 20 after whole body gamma irradiation (8 Gy). Villus height, goblet cells/villus section, total cells, mitotic cells and dead cells/crypt section in the jejunum arc good parameters for the assessment of radiation damage. There was significant decrease in the villus height, number of total cells and mitotic cells/crypt section, whereas goblet cells and dead cells showed significant increase after irradiation. Mentha pretreatment resulted in a significant increase in villus height, total cells and mitotic cells, whereas goblet cells and dead cell s showed a significant decrease from respective irradiated controls at each autopsy day. The results suggest that Mentha pretreatment provides protection against radiation induced alterations in intestinal mucosa of Swiss albino mice. |
| Page(s): | 1245-1249 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Appears in Collections: | IJEB Vol.40(11) [November 2002] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 40(11) 1245-1249.pdf | 1.09 MB | Adobe PDF | View/Open |
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