Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/23632| Title: | Evaluation of methanolic extract of Ficus platyphylla on gastrointestinal activity |
| Authors: | Amos, S Binda, L Chindo, B Akah, P Abdurahman, M Danmallam, H U Wambebe, C Gamaniel, K |
| Issue Date: | Jan-2001 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Methanolic extract of Ficus platyphylla was tested on isolated rabbit jejunum, rat duodenum and gastrointestinal motility in mice. The extract showed a biphasic effect on isolated smooth muscle. Lower concentration or extract caused contraction, while higher concentrations produced relaxation. The contractile phase was attenuated by atropine, while relaxant phase attenuated histamine induced contraction or guinea pig ileum. The extract also exhibited a dose-dependent inhibition of gastrointestinal motility. Acute toxicity test in mice established LD50 value (ip) or the extract to be 2000 mg/kg. Preliminary phytochemical screening or the extract gave positive test for flavonoids, tannins and saponins. |
| Page(s): | 63-67 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Appears in Collections: | IJEB Vol.39(01) [January 2001] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 39(1) 63-67.pdf | 1.06 MB | Adobe PDF | View/Open |
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