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http://nopr.niscpr.res.in/handle/123456789/23634| Title: | Effect of lead with vitamin E, C, or Spirulina on malondialdehyde, conjugated dienes and hydroperoxides in rats |
| Authors: | Upasani, C D Khera, A Balararnan, R |
| Issue Date: | Jan-2001 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Lead (100 ppm) was given in doubly deionised water for 30 days to one group of rats. The other groups received lead 3long with exogenous antioxidants like vitamin E (50 IU/kg), vitamin C (800 mg/kg) or Spirulina (1500 mg/kg) in food for a similar period. Levels of lipid peroxidation products such as malondialdehyde, conjugated diene and hydroperoxide were measured in liver, lung and kidney of treated rats. In lead treated animals there was a significant increase in the levels of these lipid peroxidative products. Administration of exogenous antioxidants in the lead treated animals reduced the levels of malondialdehyde, conjugated diene and hydroperoxide. It indicated that vitamin E. vitamin C and Spirulina had significant (P<0.001) antioxidant activity thereby protecting the animals from lead induced toxicity. |
| Page(s): | 70-74 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Appears in Collections: | IJEB Vol.39(01) [January 2001] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 39(1) 70-74.pdf | 1.16 MB | Adobe PDF | View/Open |
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