Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/23646
Title: Modulatory effect of quercetin on azathioprine induced membrane changes in the mouse spleen
Authors: Chitra, S
Devipriya, S
Shyamala Devi, C S
Issue Date: Feb-2001
Publisher: NISCAIR-CSIR, India
Abstract: Modulatory effect of quercetin on azathioprine induced toxic changes was studied in spleen of experimental animals. Azathioprine treatment caused an increase in serum albumin/globin ratio and a decrease in total protein in spleen tissue. An increase in a membrane bound ATPases was also noted. Supplementation of quercetin with azathioprine increased the protein content and lowered the activities of membrane ATPase in spleen. There was a decrease in serum albumin globulin ratio. It was concluded that quercetin modulated the protein and membrane bound ATPase activities and protected the spleen from azathioprine induced membrane damage.
Page(s): 132-136
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.39(02) [February 2001]

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