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http://nopr.niscpr.res.in/handle/123456789/23722| Title: | Effectiveness of ethylene glycol bis (2-aminoethyl ether) tetraacetic acid (EGTA) against cerium toxicity |
| Authors: | Shrivastava, Sadhana Mathur, R |
| Keywords: | Cerium;EGTA;Toxicity;Male mice |
| Issue Date: | Sep-2004 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int Cl7 A61 P |
| Abstract: | Therapeutic efficacy of EGTA (ethylene glycol bis (2-aminoethyl ether) tetraacetic acid) against cerium intoxicated mice was studied. Administration of cerium showed significant decrease in haemoglobin percentage, RBC counts and blood glucose level with an increase in the activity of serum transaminases and WBC counts. Decrease in the activity of alkaline phosphatase and glycogen content was noted in liver and kidney after cerium exposure. Light and electron microscopical investigations showed that these changes were recouped considerably with the administration of EGTA suggesting its therapeutic efficacy against cerium toxicity. |
| Page(s): | 876-883 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Appears in Collections: | IJEB Vol.42(09) [September 2004] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 42(9) 876-883.pdf | 2.04 MB | Adobe PDF | View/Open |
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