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http://nopr.niscpr.res.in/handle/123456789/23725| Title: | Blood anticoagulant sulphated polysaccharides of the marine green algae Codium dwarkense (Boergs.) and C. tomentosum (Huds.) Stackh. |
| Authors: | Shanmugam, M. Mody, K. H. Siddhanta, A. K. |
| Issue Date: | Apr-2001 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Cold water extracts of marine green algae Codium dwarkense and C. tomentosum were precipitated with different molar concentrations of KCI and were subjected to anion exchange and gel filtration chromatography. Both the species yielded sulphated arabinan through bioassay-guided purification and both were chemically identified as a polymer of α-L-arabinofuranose. Products were assayed for their blood anticoagulant activity using PT, APTT and TT tests and found that they differed in the potency of activity though they are chemically identical. Bioassay-guided purification of cold water extract of C. tomentosum yielded sulphated arabinan and sulphated arabinogalactan. |
| Page(s): | 365-370 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Appears in Collections: | IJEB Vol.39(04) [April 2001] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 39(4) 365-370.pdf | 1.38 MB | Adobe PDF | View/Open |
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