Modulatory potential of <i>Spirulina fusiformis </i>on testicular phosphatases in Swiss albino mice against mercury intoxication

Abstract

Administration of mercuric chloride (HgCl₂; 5.0 mg/kg body weight) to male Swiss albino-mice resulted in significantly higher levels of testicular acid phosphatase (ACP) and alkaline phosphatase (ALP) activities as compared to control. In combination group where <i>S</i>. <i>fusiformis </i>(800 mg/kg body weight) was given before and after HgCl₂ treatment, the mercury

induced toxicity reduced in terms of decreased levels of ACP and ALP activities in the testis. The animal treated with only <i>Spirulina </i>did not show any alteration in ACP and ALP values. It is suggested that oral administration of <i>Spirulina </i>can modulate mercury induced testicular toxicity.