Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/23778
Title: Protective effect of vilva juice on glycoconjugate levels in experimentally induced constipation in rats
Authors: Padmini, R
Sabitha, K E
Devi, C S Shyamala
Keywords: Constipation;Glycoconjugates;Mor-phine sulfate;Vilva juice
Issue Date: Oct-2004
Publisher: NISCAIR-CSIR, India
IPC Code: Int Cl.7 A61P
Abstract: Efficacy of vilva, a polyherbal formulation was evaluated in morphine induced constipated rats. Vilva juice, at a dose of 1.5 ml/100 g body wt was given orally for a period of 7 days. Morphine sulfate was injected to induce constipation on 8th day, 45 mm before the experiments. Protein bound glycoconjungates were estimated in intestinal tissue. Altered levels of glycoconjugates were maintained at near normalcy when pretreated with vilva juice in morphine induced rats. Histological changes were observed in the colon tissue. The damage to crypts of Liberkunn in constipated rats were found to be reduced in vilva pretreated rats. Vilva, thus, offered significant protection against morphine induced constipation by way of augmenting mucus secretion.
Page(s): 1024-1027
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.42(10) [October 2004]

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