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http://nopr.niscpr.res.in/handle/123456789/23862| Title: | Serotonin and benzylamine oxidation by type A and type B MAO of rat brain in presence of organophosphate pesticides |
| Authors: | Nag, Maitreyi Nandy, Namita |
| Issue Date: | Aug-2001 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Organophosphate (OP) pesticides, monocrotophos (MCP). dichlorvos (DDVP) and phosphamidon significantly inhibit both MAO-A and MAO-B activities in rat brain mitochondria. The inhibition or MAO-A by MCP is reversible whereas the inhibition by DDVP and phosphamidon is irreversible. MAO-B is inhibited irreversibly by all these organophosphates suggesting that the mechanism of action of or pesticides is through phosphorylation of serine residue present in active centre of MAO. |
| Page(s): | 802-806 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Appears in Collections: | IJEB Vol.39(08) [August 2001] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 39(8) 802-806.pdf | 938.77 kB | Adobe PDF | View/Open |
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