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dc.contributor.authorShrimali, Rajeev K-
dc.contributor.authorReddy, K V R-
dc.date.accessioned2013-11-21T06:00:08Z-
dc.date.available2013-11-21T06:00:08Z-
dc.date.issued2000-05-
dc.identifier.issn0975-1009 (Online); 0019-5189 (Print)-
dc.identifier.urihttp://hdl.handle.net/123456789/23954-
dc.description415-424en_US
dc.description.abstractFertilization includes sperm-egg recognition, adhesion, binding, fusion and egg activation. Integrin (ITG) receptors which are adhesion molecules are expressed on mouse, hamster and human gametes and their potential ligands also have been identified. Role of ITGs during fertilization is supported by inhibition of sperm-egg adhesion and/or fusion by means of anti-ITG mAbs, Arg-Gly-Asp (RGD) or disintegrin-like peptides. This review includes the current understanding of the molecular mechanism that regulates sperm-egg interaction and implications of this knowledge for assessing the fertility potential of men and immunocontraceptive method.en_US
dc.language.isoen_USen_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJEB Vol.38(05) [May 2000]en_US
dc.titleIntegrins and disintegrins : The candidate molecular players in sperm-egg interactionen_US
dc.typeArticleen_US
Appears in Collections:IJEB Vol.38(05) [May 2000]

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