Antifungal activity of bicyclic heterocyclic-1,2-diazole

Abstract

A novel series of heterocyclic-1,2 diazole namely N¹-iso nicotinoyl-5, 5'- dimethyl cyclohexane -4-(sulpha/substituted phenylazo) -1 ,2- diazoles have been synthesized. The compounds were screened for the anti-fungal properties against building fungi. The fungal species used for this purpose were <i>Aspergillus niger </i>and <i>Pencillium frequentans. </i>It was found that out of a series of 25 compounds, fourteen have shown significant fungicidal properties against both the above species. Minimum inhibition concentration was observed between 100 and 200 ppm for most of the compounds.