Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/24079| Title: | Radioprotective action of caffeine: Use of Saccharomyces cerevisiae as a test system |
| Authors: | Vaidya, Purva J Pasupathy, K |
| Issue Date: | Dec-2001 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Mechanism of radioprotective action of caffeine by studying they radiation -induced killing of yeast, S.cerevisae is reported. The results reveal that caffeine specifically protects aerobically (oxic) grown cells from γ - radiation and sensitizes anaerobically (hypoxic) grown cells to some extent. Using radiation sensitive strains which lack recombinational pathway, it was found that protection by caffeine was solely brought about by reducing DNA damage, rather than by interfering with DNA repair process. |
| Page(s): | 1254-1257 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Appears in Collections: | IJEB Vol.39(12) [December 2001] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 39(12) 1254-1257.pdf | 993.61 kB | Adobe PDF | View/Open |
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