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Title: Antimicrobial efficacy of a traditionally important medicinal plant - Tiliacora acuminata (Lam.) Hook. f.
Authors: Ben, C P
Remya, K P
Paul, Z Miller
Keywords: Antibacterial;Antifungal;Disc diffusion;Plant extracts;Tiliacora acuminata
Issue Date: Dec-2013
Publisher: NISCAIR-CSIR, India
IPC Code: Int. cl. (2011.01)−A61K 36/00
Abstract: The present investigation was aimed to screen the antimicrobial potential of Tiliacora acuminata (Lam.) Hook. f. against various human bacterial and fungal pathogens. Antimicrobial efficacy was performed by disc diffusion method against the bacterial pathogens, viz. Proteus mirabilis, Enterobacter aerogenes, Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus incubated for 24 h at 37° C as well as the isolates of fungal pathogens, Fusarium oxysporum, Aspergillus niger, Aspergillus terreus, Rhizopus oxysporum and Candida albicans. All the extracts of the plant, viz. acetone, chloroform, petroleum ether and distilled water, studied in the present investigation exhibited varying degree of inhibitory effect against the selected human pathogens. Further it is revealed that the activity was significant in acetone and chloroform extracts. Proteus mirabilis (fungus) and Aspergillus terreus (bacterium) forms the most susceptible microbial strains. Hence, T. acuminata forms a potentially good source of antimicrobial agent and demonstrates the importance of such plant in medicinal systems for curing various ailments.
Page(s): 358-362
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections:IJNPR Vol.4(4) [December 2013]

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