Synthesis of New Series of Heterocyclic Thiazolidin-Erylidins and Thiadiazolyl-Azitidins : Bioactive Molecules

Abstract

Four types of new substances were synthesized by selecting different types of heterocyclic compounds mainly azines and Azols. These substances are as follows: 2-(substituted eryl)-3-(azines/azols)-4-(oxothiazolidin)(1); 2-(substituted eryl)-3-azines/azols-5-erylidins-5-oxothi azolidins (2); 2-erylidinylamino-5-(azino/azolo mcthyl)-1,3,4-thiadiazoles (3) and 1[5<i>'</i>(

azino/azolo methyl)- 1<i>'</i> ,3<i>'</i> ,4<i>'</i>-thiadiazol-2<i>'</i> -oil-4-(substituted phenyl )-3 -chloro-2-oxo-azitidins (4). The structures of these substances were confirmed on the bas is of spectrometry, chemical methods and elementary analysis. Results obtained from different types were screened as antibacterial, antifungal, anti-inflammatory, wormicidal, diuretic etc.