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http://nopr.niscpr.res.in/handle/123456789/28686| Title: | Kinetic modelling of coupled transport across biological membranes |
| Authors: | Korla, Kalyani Mitra, Chanchal K |
| Keywords: | Antiport;Symport;Simulation;Octave;Michaelis-Menten kinetics |
| Issue Date: | Apr-2014 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | In this report, we have modelled a secondary active co-transporter (symport and antiport), based on the classical kinetics model. Michaelis-Menten model of enzyme kinetics for a single substrate, single intermediate enzyme catalyzed reaction was proposed more than a hundred years ago. However, no single model for the kinetics of co-transport of molecules across a membrane is available in the literature. We have made several simplifying assumptions and have followed the basic Michaelis-Menten approach. The results have been simulated using GNU Octave. The results will be useful in general kinetic simulations and modelling. |
| Page(s): | 93-99 |
| ISSN: | 0975-0959 (Online); 0301-1208 (Print) |
| Appears in Collections: | IJBB Vol.51(2) [April 2014] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJBB 51(2) 93-99.pdf | 443.54 kB | Adobe PDF | View/Open |
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