<i><span style="font-size:11.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-bidi-font-family: Mangal;mso-ansi-language:EN-GB;mso-fareast-language:EN-US;mso-bidi-language: HI" lang="EN-GB">Anethum graveolens</span></i><span style="font-size:11.0pt; font-family:"Times New Roman";mso-fareast-font-family:"Times New Roman"; mso-bidi-font-family:Mangal;mso-ansi-language:EN-GB;mso-fareast-language:EN-US; mso-bidi-language:HI" lang="EN-GB"> L. supplementation has anti-inflammatory effect in type 2 diabetic patients</span>

Abstract

This <span style="mso-bidi-language:FA" lang="EN-GB">randomized, double-blind, placebo-controlled clinical trial designed to assess the effects of <i>Anethum</i> <i>graveolens</i> L. supplementation on the pro-inflammatory biomarkers (IL-6, TNF-α) and acute phase protein hs-CRP concentrations in type 2 diabetic patients. For 8 weeks, i<span style="mso-bidi-language:FA" lang="EN-GB">ntervention group received 3.3 gm/day <i style="mso-bidi-font-style:normal">Anethum</i> powder and placebo group received same amounts starch. At the onset and at the end of study collected 5 cc blood samples. The concentration of hs-CRP was measured by spectrophotometer method. IL-6 and TNF-α were assayed using ELISA method. S<span style="mso-bidi-language: FA" lang="EN-GB">erum concentration of IL-6, TNF-α and hs-CRP decreased significantly at the end of study in intervention group (p<0.031, p<0.026, and p<0.045 respectively). Further clinical studies are needed to confirm the results.

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