Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/30082| Title: | Synthesis and antiparkinsonian activity of different pyrazolinylpyridinyl indole derivatives |
| Authors: | Kumar, Sunil Kaur, Hemlata Saxena, K K Yeshowardhana |
| Keywords: | Indoles;Pyrazolinylindoles;Pyrazolinylpyridinylindoles;Antiparkinsonian activity;Acute toxicity |
| Issue Date: | Dec-2014 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | 2-Methyl/ethyl-5-methoxy/ethoxy-3-(2-benzofuran-2-yl)-3-((2-substitutedphenylazo) pyrazolin-4-yl)indoles 3a-l have been prepared by the reaction of 2-methyl/ethyl-5-methoxy/ethoxy-3-((2-benzofuran-2-yl)-pyrazolin-4-yl)indoles 2a-d with various substituted benzenediazonium chlorides in presence of sodium acetate. Compounds 3a-l on reaction with different 4-aminopyridine and formaldehyde yield 2-methyl/ethyl-5-methoxy/ethoxy-3-((2-benzofuran-2-yl)-1-(pyridinylamino)methyl-3-substitutedphenylazo)-pyrazolin-4-yl)indoles 4a-l. All the newly synthesized compounds 3a-l and 4a-l have been screened for their antiparkinsonian activity. Structures of all the compounds are established by elemental and spectral (IR, 1H NMR and mass spectroscopic) analysis. |
| Page(s): | 1596-1605 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.53B(12) December 2014] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 53B(12) 1596-1605.pdf | 128.82 kB | Adobe PDF | View/Open |
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.