Synthesis of biologically active 4-[1-(2H-[1]-4-hydroxy- 2-oxo-benzopyran- 3-y1) methylidene]-2-phenyl-4H-oxazol-5-ones and [l,2,4]triazine-6-one and its derivatives

Mulwad, V; Satwe, D S

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Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/30694

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DC Field	Value	Language
dc.contributor.author	Mulwad, V	-
dc.contributor.author	Satwe, D S	-
dc.date.accessioned	2015-02-27T04:34:36Z	-
dc.date.available	2015-02-27T04:34:36Z	-
dc.date.issued	2006-05	-
dc.identifier.issn	0975-0983(Online); 0376-4699(Print)	-
dc.identifier.uri	http://hdl.handle.net/123456789/30694	-
dc.description	1210-1215	en_US
dc.description.abstract	3-Formyl-2H-[1]-4-hydroxy-2-oxo-benzopyrans 1a-d on treatment with N-benzoyl glycine in the presence of sodium acetate and acetic anhydride give 4-[1-(2H-[1]-4-hydroxy-2-oxo-benzopyran-3-yl)methylidene]-2-phenyl-4H-oxazol-5-ones 2a-d which upon treatment with 4,7-dimethyl 6-coumarin hydrazine hydrochloride/phenyl hydrazine give 2-[4,7-dimethyl 2H-[1]-2-oxo-benzopyran-6-yl]/pheny1-5-[1-(2H - [1]-4-hydroxy-2-oxo-benzopyran-3-yl)methylidene]-3-phenyl-2,5-dihydro -1H-[1,2,4] triazine-6-ones 3a-h. Acetylation of 3a-h gave 1-acetyl-2-[4,7-dimethyl 2H-[1]-2-oxo-benzopyran-6-yl]/phenyl- 5-[2H-[1]-4-hydroxy-2-oxo-benzopyran-3-yl] rnethylidene]-3-phenyl-[1,2,4]-triazine-6-ones 4a-h. The structures of all these compounds have been established on the basis of the spectral and analytical data. All compounds have been screened for their antimicrobial activity and have been found to exhibit significant activity.	en_US
dc.language.iso	en_US	en_US
dc.publisher	NISCAIR-CSIR, India	en_US
dc.relation.ispartofseries	Int.CI.⁸ C 07 D	en_US
dc.rights	CC Attribution-Noncommercial-No Derivative Works 2.5 India	en_US
dc.source	IJC-B Vol.45B(05) [May 2006]	en_US
dc.subject	N-benzoyl glycine	en_US
dc.subject	4H-oxazol-5-ones	en_US
dc.subject	Phenyl hydrazine	en_US
dc.subject	[1,2,4]triazine 6-ones	en_US
dc.subject	Antimicrobial activity	en_US
dc.title	Synthesis of biologically active 4-[1-(2H-[1]-4-hydroxy- 2-oxo-benzopyran- 3-y1) methylidene]-2-phenyl-4H-oxazol-5-ones and [l,2,4]triazine-6-one and its derivatives	en_US
dc.type	Article	en_US
Appears in Collections:	IJC-B Vol.45B(05) [May 2006]

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