Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/30719| Title: | Grignard reagent and Green Chemistry: Mechanistic studies to understand the molecular origins of selectivity in the formation of RMgX |
| Authors: | Hazimeh, Hassan Mattalia, Jean-Marc Attolini, Mireille Bodineau, Nicolas Marchi-Delapierre, Kishan Handoo Caroline |
| Keywords: | Green chemistry;Grignard reagent;Mechanistic study |
| Issue Date: | Oct-2006 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int. CI8 C07B49 |
| Abstract: | Controlling selectivity is one or the important keywords in the development of Green Chemistry. The mechanistic study of the formation of RMgX with the aim of understanding at which step(s) the selectivity is settled shows that there is room for basic research in a field too often considered as the simple development of new recipes. One of the most widely used reactions in synthetic studies still offers fascinating conundrums when one tries to answer the apparently simple question: at which step(s) docs the formation of by-products coexisting with RMgX occur? Here the illustration of this statement is given by studying the patterns of reactivity of aliphatic and aromatic radical clock halides toward magnesium or potassium. The importance of using the concepts developed by electrochemists to rationalize the selectivity observed at cathodes or anodes for understanding selectivity observed in the reactive dissolution of metals is stressed. |
| Page(s): | 2270-2280 |
| ISSN: | 0042-6075 |
| Appears in Collections: | IJC-B Vol.45B(10) [October 2006] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 45B(10) 2270-2280.pdf | 2.6 MB | Adobe PDF | View/Open |
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.