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http://nopr.niscpr.res.in/handle/123456789/30841| Title: | Formulation and in vitro characterization of niosomes containing 5-fluorouracil |
| Authors: | Parikh, Jolly R Murthy, R S R Parikh, R H |
| Issue Date: | Jul-1998 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The present work describes preparation and in vitro characterization of niosomes containing 5fluorouracil (5-FU) using non-ionic surfactant series of sorbitan esters (Spans) by thin film hydration method. Niosomes prepared from Span 40 and Span 60 exhibit higher entrapment of 5-FU as compared to niosomes prepared from Span 80 and Span 85. Cholesterol increases the entrapment of 5-FU into niosomes. Dicetyl phosphate reduces the size of niosomes. The leakage of 5-FU from niosomes reduces on freeze drying. |
| Page(s): | 192-194 |
| ISSN: | 0975-0991 (Online); 0971-457X (Print) |
| Appears in Collections: | IJCT Vol.05(4) [July 1998] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCT 5(4) 192-194.pdf | 213.25 kB | Adobe PDF | View/Open |
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