Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/31493| Title: | Cytotoxic triterpenoids from Ficus pomifera Wall. |
| Authors: | Wangkheirakpam, Sujata D Wadawale, Amey Leishangthem, Surendrajit S Gurumayum, Jitendra S Laitonjam, Warjeet S |
| Keywords: | Ficus;Moraceae;Triterpenoid;Mo-Kα X ray crystallography;Antioxidant;Cytotoxic |
| Issue Date: | May-2015 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | 3β-Acetoxyurs-12-ene 1, 3β-hydroxyurs-12-ene 2 and three other triterpenoids, 3β-hydroxyurs-12-en-27-oic acid 3, 3β-hydroxyolean-12-en-27-oic acid 4 and 3α-acetoxyolean-12-en-27-oic acid 5 have been isolated from Ficus pomifera Wall. Their chemical structures have been established by spectroscopic analysis. The structure of compound 1 is confirmed with single-crystal X-ray analysis. Compound 1 has been characterised for properties such as particle size and photoluminescence with fluorescence spectroscopy and transmission electron microscopy (TEM) for applications comparable to those of nanocomposites. The size has been characterised in the range of nanoparticles, and the compound exhibit fluorescence. Compounds 1 and 2 show cytotoxic activity in an MTT assay on human lung cancer cell line A549, exhibiting IC50 values of 15 µg/mL and 3 µg/mL, respectively. |
| Page(s): | 676-681 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.54B(05) [May 2015] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 54B(5) 676-681.pdf | 224.52 kB | Adobe PDF | View/Open |
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.