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http://nopr.niscpr.res.in/handle/123456789/33034| Title: | Carbohydrate hydrolyzing enzymes inhibitory and free radical scavenging activities of substituted 2H-chromene-3-carboxylates, 2H-chromenyl Knoevenagel derivatives and 6H-chromenoquinolinones |
| Authors: | Vishnu, S Srikanth, P Tiwari, Ashok K Kumar, D Anand Raju, B China |
| Keywords: | 2H-Chromene-3-carboxylates;2H-chromenyl Knoevenagel derivatives;6H-chromenoquino-linones;Salicylaldehydes;4-chloro-3-formylcoumarin;Anti-oxidant;Anti-diabetic |
| Issue Date: | Nov-2015 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Three series of compounds namely ethyl 2-hydroxy-2-(trifluoromethyl)-2H-chromene-3-carboxylates 3a-q, 2H-chromenyl Knoevenagel derivatives 7a-j and 6H-chromenoquinolinones 9a-l have been prepared. The synthesized compounds 3a-q, 7a-j and 9a-g have been screened for anti-oxidant and anti-diabetic activity. Compound 3i shows the most potent ABTS inhibitory activity when compared to trolox. Compounds 3b, 3d, 3j and 3l show α-amylase inhibitory activity. |
| Page(s): | 1332-1341 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.54B(11) [November 2015] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 54B(11) 1332-1341.pdf | 169.32 kB | Adobe PDF | View/Open |
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