Phenoxazinone synthase activity of a mononuclear cobalt(III) complex

Abstract

<span style="font-size:9.0pt;font-family: " times="" new="" roman","serif";mso-fareast-font-family:"times="" roman";mso-ansi-language:="" en-us;mso-fareast-language:en-us;mso-bidi-language:ar-sa"="" lang="EN-US">The trivalent cobalt complex, [Co(HL)₂](OAc).H₂O (<b style="mso-bidi-font-weight: normal">1</b>) [H₂L = <i>N</i>-(2-hydroxyethyl)-3-methoxysalicylaldimine], behaves as an effective catalyst towards oxidative dehydrogenation of <i style="mso-bidi-font-style:normal">o</i>-aminophenol to <span style="font-size:9.0pt;font-family:" times="" new="" roman","serif";mso-fareast-font-family:="" "times="" roman";mso-ansi-language:en-in;mso-fareast-language:en-us;="" mso-bidi-language:ar-sa"="">2-aminophenoxazine-3-one in aerial<span style="font-size:9.0pt;font-family:" times="" new="" roman","serif";="" mso-fareast-font-family:"times="" roman";mso-ansi-language:en-us;mso-fareast-language:="" en-us;mso-bidi-language:ar-sa"="" lang="EN-US"> oxygen. The reaction follows Michaelis-Menten enzymatic reaction kinetics in methanol with turnover number (<i style="mso-bidi-font-style:normal">K</i>_cat) = <span style="font-size:9.0pt;font-family:" times="" new="" roman","serif";mso-fareast-font-family:="" "times="" roman";mso-ansi-language:en-in;mso-fareast-language:en-us;="" mso-bidi-language:ar-sa;mso-bidi-font-weight:bold"="">2.83×10⁴ <span style="font-size:9.0pt;font-family:" times="" new="" roman","serif";="" mso-fareast-font-family:"times="" roman";mso-ansi-language:en-us;mso-fareast-language:="" en-us;mso-bidi-language:ar-sa"="" lang="EN-US">h^-1.</span></span></span></span></span>