<span style="font-size:11.0pt;font-family: "Times New Roman","serif";mso-fareast-font-family:"Times New Roman";mso-bidi-font-family: Mangal;mso-ansi-language:EN-GB;mso-fareast-language:EN-US;mso-bidi-language: HI" lang="EN-GB">Comprehensive investigation of free radical quenching potential, total phenol, flavonoid and saponin content, and chemical profiles of twelve <i style="mso-bidi-font-style:normal">Chlorophytum </i><span style="mso-bidi-font-style:italic">Ker Gawl. species</span></span>

Abstract

<span style="font-size:11.0pt;font-family: " times="" new="" roman","serif";mso-fareast-font-family:"times="" roman";mso-bidi-font-family:="" mangal;mso-ansi-language:en-gb;mso-fareast-language:en-us;mso-bidi-language:="" hi"="" lang="EN-GB">India represents eighteen species of genus <i style="mso-bidi-font-style: normal">Chlorophytum </i><span style="mso-bidi-font-style:italic">Ker Gawl., which are cumulatively known and used as <i style="mso-bidi-font-style:normal">Safed Musali</i>. Out of these, <i style="mso-bidi-font-style:normal">Chlorophytum borivilianum </i><span style="mso-bidi-font-style:italic">Santapau & R.R.Fern is extensively utilized by virtue of a wide array of bioactivities. In the present study, comparative analysis of twelve species of the genus <i style="mso-bidi-font-style:normal">Chlorophytum</i><span style="mso-bidi-font-style:italic"> including <i style="mso-bidi-font-style:normal">C. borivilianum </i>was done to find its alternative with respect to phytochemical content and antioxidant potential. Among all species analyzed, <i style="mso-bidi-font-style:normal">C. amaniense </i>Engl. showed highest phenol (654.5 mg/g), flavonoid (191.1 mg/g) and saponin (7.42 %) contents. Highest DPPH free radical quenching activity was observed in <i style="mso-bidi-font-style:normal">C. amaniense </i>Engl.<i style="mso-bidi-font-style:normal"> </i><span style="mso-bidi-font-style:italic">(86.97 %) which was nearly 30 % more than that of <i style="mso-bidi-font-style:normal">C. borivilianum</i>. HPTLC chemical fingerprint of all the C<i>hlorophytum</i> species was established showing a visible difference in the band pattern and intensities. HPTLC fingerprint of <i style="mso-bidi-font-style:normal">C. amaniense </i><span style="mso-bidi-font-style:italic">showed presence of maximum number of bands with high intensity. GC-MS analysis of all the extracts of twelve species revealed presence of 35 different molecules and/or fragments of molecules. Present study may be the first systematic and comparative evaluation of the genus <i style="mso-bidi-font-style: normal">Chlorophytum</i>, indicates <i style="mso-bidi-font-style:normal">C. amaniense </i><span style="mso-bidi-font-style:italic">Engl.<i style="mso-bidi-font-style:normal"> </i>as an alternative to <i style="mso-bidi-font-style:normal">C. borivilianum.</i></span></span></span></span></span></span></span>