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http://nopr.niscpr.res.in/handle/123456789/34579| Title: | Microfouling inhibitors from the Indian gorgonian Subergorgia reticulata (Ellis and Solander, 1786) |
| Authors: | Mol, V.P. Limna Abhilash, K.R. Raveendran, T.V. Parameswaran, P.S. |
| Keywords: | Biofouling;Microfouling;Antifouling;Subergorgia reticulata;Calamenenes |
| Issue Date: | Nov-2014 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Antifouling research currently focuses on greener ways of biofouling control in view of the International Maritime Organisation (IMO) imposed regulations on toxic biocides. Microfouling, the initial phase of fouling, is an important target to prevent further macrofouling assemblage. In this perspective, the antimicrofouling potential of three calamenene derivatives (2-methoxy calamenene, 1; 2,5-dimethoxy calamenene, 2 and 2-methoxy, 5-acetoxy calamenene, 3 isolated from the Indian gorgonian Subergorgia reticulata was investigated. These compounds inhibited growth of five fouling bacterial strains (Bacillus megaterium, Vibrio furnissii, V. fischeri, V. gazogenes and V. parahaemolyticus) as well as the two species of diatoms (Amphora coffeaeformis and Navicula transitans). Of these, the highest activity was exhibited by compound 3 against B. megaterium (MIC, 12.5µg) and N. transitans (EC50,14µg/ml). The environmental-compatibility of this compound was evidenced from the non-toxicity to B. amphitrite nauplii (IC50 1µg/ml) and Artemia sp. nauplii (IC50 0.6µg/ml). Analysis of structure-activity relationship suggested that the acetoxy group present in 3 may be responsible for the comparatively high antifouling activity exhibited by this compound. |
| Page(s): | 2094-2100 |
| ISSN: | 0975-1033 (Online); 0379-5136 (Print) |
| Appears in Collections: | IJMS Vol.43(11) [November 2014] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJMS 43(11) 2094-2100.pdf | 231.37 kB | Adobe PDF | View/Open |
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