<span style="font-size:15.0pt;line-height: 115%;font-family:"Times New Roman","serif";mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA" lang="EN-US">Antimicrobial effect of <i>Ulva fasciata</i> Delile, 1813 solvent extracts against multidrug resistant human pathogenic bacteria and fish pathogens</span>

Abstract

Macroalga, <i>U</i><i style="mso-bidi-font-style: normal">lva fasciata</i> was collected, extracts prepared, fractionated using different solvent systems and screened for their antibiotic sensitivity against pathogenic bacterial strains. M<span style="mso-bidi-font-style:italic">ethanol extract of<i> </i><i style="mso-bidi-font-style:normal">U. fasciata</i> inhibited 66% of Gram +^ve bacteria, whereas the activity was less towards aqueous extract. Inhibitory potential of methanol extract of <i style="mso-bidi-font-style:normal">U. fasciata</i> was high with 78.5 mm² towards Gram +^ve strain of <i style="mso-bidi-font-style:normal">Staphylococcus aureus </i>at 20^oC than at 30^oC<i style="mso-bidi-font-style:normal"> </i>compared to the commercial antibiotics. Among the active fractions, s<span style="mso-bidi-font-weight:bold">uccessful inhibition was noted in FD2 - CH₂Cl₂: MeOH (1:1), M₄ - Methanol - Acn and <span style="mso-bidi-font-weight: bold">MD1-MeOH - dcm fractions. T<span style="mso-bidi-font-style:italic">he FD2 (chloroform and methanol combinations) fraction against MOF 1 (shrimp, <i style="mso-bidi-font-style:normal">Penaeus monodon</i> isolate)<b style="mso-bidi-font-weight:normal"> </b><span style="mso-bidi-font-style:italic">and MOF 2 (Clown fish isolate)<b style="mso-bidi-font-weight:normal"> </b><span style="mso-bidi-font-style:italic">isolates were found to be most active with highest inhibitory zone of ≥143.06 mm².<span style="mso-bidi-font-weight:bold">

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