<span style="font-size:15.0pt;mso-bidi-font-family: "Times New Roman"" lang="EN-GB">Characterization and antimicrobial activity of <i>Streptomyces </i>sp. DOSMB-A107 <span style="font-size:15.0pt;font-family:"Times New Roman","serif"; mso-fareast-font-family:"Times New Roman";mso-ansi-language:EN-GB;mso-fareast-language: EN-US;mso-bidi-language:HI" lang="EN-GB">isolated from mangrove sediments of Andaman Island, India</span></span></p>

Abstract

<span style="font-size:9.0pt;font-family:" times="" new="" roman","serif";="" mso-fareast-font-family:"times="" roman";mso-bidi-font-family:mangal;="" mso-ansi-language:en-gb;mso-fareast-language:en-us;mso-bidi-language:hi"=""> In the present study, focused the antimicrobial compound production by the marine actinobacteria isolated from the mangrove sediments of Andaman Island. <i>Streptomyces </i>sp. DOSMB-A107 isolated from mangrove sediments of Andaman Island was identified by morphological, chemistry of cell wall and molecular characterization. Bioactive compounds were extracted with five different solvents and were identified using GC-MS analysis. Among the five different solvents ethyl acetate extract showed maximum activity against eleven bacteria and six fungal pathogens than other solvents. Twelve compounds were identified, off the following eight compounds such as 2-Butanol, 2-nitroso-, acetate(ester), Phenylethyl Alcohol, Phenol, 2,4-bis(1,1- dimethylethyl)-, 1-Hexadecanol, Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3- (2-methylpropyl)-, 1Hentetracontanol, 1-Eicosanol, Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5' (phenylmethyl)-, (5'à)- were identified as anti-infective agent. Ethyl acetate would be a suitable solvent for the extraction of antimicrobial agents from <i>Streptomyces</i>.</span>