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http://nopr.niscpr.res.in/handle/123456789/39859| Title: | Why zinc in zinc-fingers ? |
| Authors: | Reddy, P Rabindra |
| Issue Date: | Jan-1998 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | It is found that Zn complex based units are present in a number of nucleic acid binding and gene regulatory proteins. The Zn is a crucial component of the tertiary structure of "Zn-finger" since the two invariant cysteines and two invariant histidines which constitute each of the nine tandem repeats of amino acid motif are coordinated to Zn in a tetrahedral configuration (Zn-core). An attempt has been made to reason why Zn is present in "Zn-fingers" based on the assessment of the stability aspect of the core with Zn and Co. |
| Page(s): | 53-55 |
| ISSN: | 0975-0975(Online); 0376-4710(Print) |
| Appears in Collections: | IJC-A Vol.37A(01) [January 1998] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCA 37A(1) 53-55.pdf | 302.5 kB | Adobe PDF | View/Open |
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